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  • anti-Collagen II antibody [5B2.5]
  • publication_list (2 Publications)
  • Cat. No: ARG62450 　(Mouse mAb)
  • Reactivity: Hu, Ms, Chk, Pig, Rb
  • Application: ICC/IF, IHC-Fr, IHC-P, WB
  • Specificity: This antibody is highly specific to type II collagen and shows no cross-reaction with types I, III, IV, V, VI, IX, X, or XI. In Western blotting, this antibody reacts with the TCA fragment of lathyritic type II collagen after digestion with mammalian collagenase. It does not react with pepsin-digested type II collagen.
  • Conjugation: Un-conjugated
  • anti-Insulin antibody
  • Cat. No: ARG62502 　(Guinea pig pAb)
  • Reactivity: Hu, Ms, Rat, Hm
  • Application: FACS, ICC/IF, IHC-Fr, IHC-P, IP
  • Conjugation: Un-conjugated
  • anti-Myc tag antibody [9E10]
  • publication_list (1 Publications)
  • Cat. No: ARG62962 　(Mouse mAb)
  • Reactivity: Other
  • Application: FACS, IHC-P, IP, WB, CyTOF®-candidate
  • Specificity: The clone 9E10 may be used to detect the c-Myc tag.
    The c-myc gene (8q24 on human chromosome) is the cellular homologue of the v-myc gene originally isolated from an avian myelocytomatosis virus. The c-Myc protein is a transcription factor (nuclear localization). c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin-dependent kinase, ERK2 and C-Jun N-terminal Kinase (JNK) in cell proliferation and cell cycle regulation. In normal cells the expression of c-Myc is tightly regulated but in human cancers c-Myc is frequently deregulated. c-Myc is also essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells.
  • Conjugation: Un-conjugated
  • anti-p53 antibody [BP53-12]
  • Cat. No: ARG63081 　(Mouse mAb)
  • Reactivity: Hu, NHuPrm
  • Application: ELISA, FACS, ICC/IF, IHC-P, IP, WB
  • Specificity: The clone BP53-12 recognizes defined epitope (aa 16-25) on human p53, a 50 kDa tumour suppressor found in increased amounts in a wide variety of transformed cells; it is frequently mutated or inactivated in many types of cancer.
  • Conjugation: Un-conjugated
  • anti-Ki-67 antibody [Ki-67]
  • Cat. No: ARG65620 　(Mouse mAb)
  • Reactivity: Hu, Bov
  • Application: FACS, ICC/IF, IHC-P, WB, CyTOF®-candidate
  • Specificity: This antibody recognizes Ki-67 antigen, a non-histone nuclear protein expressed exclusively in proliferating cells.
  • Conjugation: Un-conjugated
  • anti-CD44 antibody [IM7]
  • Cat. No: ARG65642 　(Rat mAb)
  • Reactivity: Hu, Ms, Cat, Dog, Hrs
  • Application: FACS, ICC/IF, IHC-Fr, IHC-P, IP, WB, CyTOF®-candidate
  • Specificity: Reacts with CD44 antigen (Phagocyte glycoprotein 1), an 80-95 kDa transmembrane glycoprotein (hyaladherin family) present on the most of cells and tissues (leukocytes, endothelial cells, mesenchymal cells, etc.); it is negative on platelets and hepatocytes. The antibody reacts with all isoforms of mouse CD44.
  • Conjugation: Un-conjugated
  • anti-PUMA antibody
  • Cat. No: ARG57486 　(Rabbit pAb)
  • Reactivity: Hu, Ms, Rat
  • Application: FACS, ICC/IF, IHC-P, WB
  • Specificity: This antibody detects endogenous levels of total PUMA.
  • Conjugation: Un-conjugated
  • anti-RhoA + RhoB + RhoC antibody
  • Cat. No: ARG57488 　(Rabbit pAb)
  • Reactivity: Hu, Ms, Rat
  • Application: FACS, ICC/IF, IHC-P, WB
  • Specificity: This antibody detects endogenous levels of total RhoA + RhoB + RhoC.
  • Conjugation: Un-conjugated
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