Search Result - Primary Antibodies
There are 63 results for "Myc"
- anti-c-Myc antibody [JAC6]
- Cat. No: ARG24107 (Rat mAb)
- Reactivity: Hu
- Application: ICC/IF, IHC-Fr, IP, WB
- Conjugation: Un-conjugated
- anti-c-Myc antibody [9E10.3]
- Cat. No: ARG56063 (Mouse mAb)
- Reactivity: Hu
- Application: IHC-P
- Conjugation: Un-conjugated
- anti-Myc tag antibody [9E10]
-
(1 Publications)
- Cat. No: ARG62962 (Mouse mAb)
- Reactivity: Other
- Application: FACS, IHC-P, IP, WB, CyTOF®-candidate
- Specificity: The clone 9E10 may be used to detect the c-Myc tag.
The c-myc gene (8q24 on human chromosome) is the cellular homologue of the v-myc gene originally isolated from an avian myelocytomatosis virus. The c-Myc protein is a transcription factor (nuclear localization). c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin-dependent kinase, ERK2 and C-Jun N-terminal Kinase (JNK) in cell proliferation and cell cycle regulation. In normal cells the expression of c-Myc is tightly regulated but in human cancers c-Myc is frequently deregulated. c-Myc is also essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells. - Conjugation: Un-conjugated
- anti-Myc tag antibody [Myc.A7]
-
(2 Publications)
- Cat. No: ARG62341 (Mouse mAb)
- Reactivity: Other
- Application: Dot, ELISA, ICC/IF, IP, WB
- Specificity: Recognizes the N-terminal or C-terminal Myc-tagged fusion proteins
- Conjugation: Un-conjugated
- anti-Myc tag antibody
-
(1 Publications)
- Cat. No: ARG54503 (Goat pAb)
- Reactivity: Other
- Application: ELISA, ICC/IF, IHC-P, WB
- Conjugation: Un-conjugated
- anti-Myc tag antibody (Agarose)
- Cat. No: ARG54505 (Goat pAb)
- Reactivity: Other
- Application: IP
- Conjugation: Agarose
- anti-Myc tag antibody (HRP)
- Cat. No: ARG54507 (Goat pAb)
- Reactivity: Other
- Application: ELISA, ICC/IF, IHC-P, WB
- Conjugation: HRP
- anti-Myc tag antibody
- Cat. No: ARG55730 (Goat pAb)
- Reactivity: Other
- Application: WB
- Specificity: This antibody recognizes recombinant proteins containing EQKLISEEDL epitope tag fused to either amino- or carboxy-terminal of targeted proteins in transfected cells.
- Conjugation: Un-conjugated
- anti-Myc tag antibody [9E10] (HRP)
- Cat. No: ARG55929 (Mouse mAb)
- Reactivity: Other
- Application: WB
- Conjugation: HRP
- anti-Myc tag antibody [9E10] (FITC)
- Cat. No: ARG53920 (Mouse mAb)
- Reactivity: Other
- Application: FACS
- Specificity: The clone 9E10 may be used to detect the c-Myc tag.
The c-myc gene (8q24 on human chromosome) is the cellular homologue of the v-myc gene originally isolated from an avian myelocytomatosis virus. The c-Myc protein is a transcription factor (nuclear localization). c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin-dependent kinase, ERK2 and C-Jun N-terminal Kinase (JNK) in cell proliferation and cell cycle regulation. In normal cells the expression of c-Myc is tightly regulated but in human cancers c-Myc is frequently deregulated. c-Myc is also essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells. - Conjugation: FITC
