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  • anti-CD59 antibody [MEM-43] (PE)
  • Cat. No: ARG53882 　(Mouse mAb)
  • Reactivity: Hu
  • Application: FACS
  • Specificity: The clone MEM-43 reacts with well defined epitope (W40, R-53) on CD59 (Protectin), an 18-20 kDa glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed on all hematopoietic cells; it is widely present on cells in all tissues.
    HLDA IV; WS Code NL 705
    HLDA V; WS Code AS S013
    HLDA V; WS Code BP BP345
    HLDA V; WS Code T T-103
  • Conjugation: PE
  • anti-CD8 antibody [MEM-31] (PE)
  • Cat. No: ARG53901 　(Mouse mAb)
  • Reactivity: Hu
  • Application: FACS
  • Specificity: The clone MEM-31 recognizes a conformationally-dependent epitope of CD8, a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 is a disulfide-linked dimer and exists as a CD8 alpha/alpha homodimer or CD8 alpha/beta heterodimer (each monomer approx. 32-34 kDa).
    does not react with formaldehyde-fixed cells; negative in Western Blotting application.

    HLDA III; WS Code T 575
  • Conjugation: PE
  • anti-CD98 antibody [MEM-108] (PE)
  • Cat. No: ARG53917 　(Mouse mAb)
  • Reactivity: Hu
  • Application: FACS
  • Specificity: The clone MEM-108 reacts with CD98, a 125 kDa disulfide-linked heterodimer (80 kDa glycosylated heavy chain + 45 kDa non-glykosylated light chain). CD98 is expressed on T lymphocytes (upon activation) and activated NK cells; it is also present at low levels on B lymphocytes, NK cells, monocytes and platelets.
    HLDA VI; WS Code BP 409
    HLDA VI; WS Code NL N-L017
  • Conjugation: PE
  • anti-Myc tag antibody [9E10] (FITC)
  • Cat. No: ARG53920 　(Mouse mAb)
  • Reactivity: Other
  • Application: FACS
  • Specificity: The clone 9E10 may be used to detect the c-Myc tag.
    The c-myc gene (8q24 on human chromosome) is the cellular homologue of the v-myc gene originally isolated from an avian myelocytomatosis virus. The c-Myc protein is a transcription factor (nuclear localization). c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin-dependent kinase, ERK2 and C-Jun N-terminal Kinase (JNK) in cell proliferation and cell cycle regulation. In normal cells the expression of c-Myc is tightly regulated but in human cancers c-Myc is frequently deregulated. c-Myc is also essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells.
  • Conjugation: FITC
  • anti-HLA DP + DR antibody [HL-38] (PE)
  • Cat. No: ARG53942 　(Mouse mAb)
  • Reactivity: Hu, Pig
  • Application: FACS
  • Specificity: The clone HL-38 recognizes common epitope on beta-chain of human HLA-DR and HLA-DP. DR and DP are the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC; dendritic cells, B lymphocytes, monocytes, macrophages).
  • Conjugation: PE
  • anti-Intra Acrosomal Protein antibody [Hs-14] (FITC)
  • Cat. No: ARG53952 　(Mouse mAb)
  • Reactivity: Hu, Ms
  • Application: FACS
  • Specificity: The clone Hs-14 reacts with a 220 kDa testis-specific human intra-acrosomal protein associated with the membranes of the acrosomal vesicle._x000D_
  • Conjugation: FITC
  • anti-NTAL / LAB antibody [NAP-07] (PE)
  • Cat. No: ARG53957 　(Mouse mAb)
  • Reactivity: Hu, Ms
  • Application: FACS
  • Specificity: The clone NAP-07 reacts with Non-T cell activation linker (NTAL), also known as LAB (linker of activated B cells), a 25 - 30 kDa transmembrane adaptor protein present in membrane microdomains (rafts) of B lymphocytes, NK cells and myeloid cells.
  • Conjugation: PE
  • anti-p53 antibody [BP53-12] (FITC)
  • Cat. No: ARG53958 　(Mouse mAb)
  • Reactivity: Hu, NHuPrm
  • Application: FACS
  • Specificity: The clone BP53-12 recognizes defined epitope (aa 16-25) on human p53, a 50 kDa tumour suppressor found in increased amounts in a wide variety of transformed cells; it is frequently mutated or inactivated in many types of cancer.
  • Conjugation: FITC
  • anti-CD253 / TRAIL antibody [2E5] (PE)
  • Cat. No: ARG54196 　(Mouse mAb)
  • Reactivity: Hu
  • Application: FACS
  • Specificity: The clone 2E5 reacts with TRAIL (APO-2L), a 21 kDa cytotoxic protein, activator of rapid apoptosis in tumor cells. TRAIL is mainly expressed in spleen, lung, prostate and also in many other tissues.
  • Conjugation: PE
  • anti-Myc tag antibody [9E10] (biotin)
  • Cat. No: ARG54213 　(Mouse mAb)
  • Reactivity: Other
  • Application: FACS
  • Specificity: The antibody 9E10 may be used to detect the cMyc tag.
    The cmyc gene (8q24 on human chromosome) is the cellular homologue of the vmyc gene originally isolated from an avian myelocytomatosis virus. The cMyc protein is a transcription factor (nuclear localization). cMyc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of cMyc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclindependent kinase, ERK2 and CJun Nterminal Kinase (JNK) in cell proliferation and cell cycle regulation. In normal cells the expression of cMyc is tightly regulated but in human cancers cMyc is frequently deregulated. cMyc is also essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells.
  • Conjugation: Biotin
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