ARG83744
Glucagon ELISA Kit
Glucagon ELISA Kit for ELISA and Bovine,Dog,Human,Mouse,Pig,Rat
Overview
| Product Description | ARG83744 Glucagon ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human, Rat, Mouse, Pig, Bovine, Dog Glucagon in serum and plasma. |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Bov, Dog, Pig |
| Tested Application | ELISA |
| Specificity | Cross Reactivity: Glucagon 100% Oxyntomodulin 100% Not Cross Reactivity: Glucagon-Like Peptide-1 (GLP-1) 0% Glucagon-Like Peptide-2 (GLP-2) 0% Insulin 0% Somatostatin 0% Amylin 0% CGRP 0% Amylin 0% PPP 0% Pro-Insulin 0% |
| Target Name | Glucagon |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 0.16 ng/ml |
| Sample Type | Serum and Plasma |
| Standard Range | 0.16 - 3.74 ng/ml |
| Sample Volume | 50 μl |
| Precision | Intra-Assay CV: <10% Inter-Assay CV: <15% |
| Alternate Names | GCG; Glucagon; GLP-1; GLP1; GLP2; GRPP; Glicentin-Related Polypeptide; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Preproglucagon; Pro-Glucagon |
Application Instructions
| Assay Time | 4.5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | GCG |
| Gene Full Name | Glucagon |
| Background | The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008] |
| Function | Plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. [Uniprot] |
| Cellular Localization | Secreted. [Uniprot] |
| PTM | Amidation, Cleavage on pair of basic residues, Phosphoprotein. [Uniprot] |
