ARG83738
Human L22 RA2/IL-22BP ELISA Kit
Human L22 RA2/IL-22BP ELISA Kit for ELISA and Human
Overview
| Product Description | ARG83738 Human L22 RA2/IL-22BP ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human L22 RA2/IL-22BP in serum and plasma (heparin, EDTA), cell culture supernatants |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Target Name | L22 RA2/IL-22BP |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 25 pg/ml |
| Sample Type | serum and plasma (heparin, EDTA), cell culture supernatants |
| Standard Range | 46.9 pg/ml - 3000 pg/ml |
| Sample Volume | 100 μl |
| Precision | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| Alternate Names | IL22RA2; Interleukin 22 Receptor Subunit Alpha 2; CRF2-S1 ; IL-22BP; Cytokine Receptor Family Type 2, Soluble 1; Interleukin-22 Receptor Subunit Alpha-2; Cytokine Receptor Class-II Member 10; Interleukin 22 Receptor, Alpha 2; IL-22R-Alpha-2; IL-22RA2; CRF2-10; Cytokine Receptor Family 2 Member 10; Interleukin 22-Binding Protein; IL-22 Receptor Subunit Alpha-2; Interleukin-22-Binding Protein; ZCYTOR16; ZcytoR16; IL22BP; CRF2X |
Application Instructions
| Assay Time | ~ 5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 4°C, -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q969J5 Human Interleukin-22 receptor subunit alpha-2 |
|---|---|
| Gene Symbol | IL22RA2 |
| Gene Full Name | Interleukin 22 Receptor Subunit Alpha 2 |
| Background | This gene encodes a member of the class II cytokine receptor family. The encoded soluble protein specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor. The encoded protein may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013] |
| Function | Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses. Isoform 1 may play a role in establishing and maintaining successful pregnancy. [Uniprot] |
| Cellular Localization | Secreted. [Uniprot] |
| PTM | Disulfide bond; Glycoprotein. [Uniprot] |
| Title | Download Link |
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| ARG83738 Human L22 RA2IL-22BP ELISA Kit-User manual |
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