ARG70598
Human NCR1 recombinant protein (Avi-His-tagged, C-ter)
Human NCR1 recombinant protein (Avi-His-tagged, C-ter) for SDS-PAGE
Overview
| Product Description | CHO expressed, Avi-His-tagged (C-ter) Human NCR1 recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | NCR1 |
| Species | Human |
| A.A. Sequence | Gln22 - Arg258 |
| Expression System | CHO |
| Alternate Names | NCR1; natural cytotoxicity triggering receptor 1; CD antigen CD335; Natural killer cell p46-related protein; Lymphocyte antigen 94 homolog; Natural cytotoxicity triggering receptor 1; hNKp46; NKP46; NKp46; NK cell-activating receptor; LY94; CD335; NK-p46 |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | > 85% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | NCR1 |
|---|---|
| Gene Full Name | natural cytotoxicity triggering receptor 1 |
| Background | Predicted to be involved in immune response-regulating signaling pathway. Predicted to act upstream of or within defense response to virus and detection of virus. Predicted to be located in cell surface. Predicted to be part of SWI/SNF complex. Predicted to be active in plasma membrane. Biomarker of acquired immunodeficiency syndrome; anogenital venereal wart; hepatitis C; and lymphoproliferative syndrome. [provided by Alliance of Genome Resources, Feb 2025] |
| Function | Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. [UniProt] |
| Cellular Localization | Cell membrane; Membrane. [UniProt] |
| PTM | N-glycosylated. O-glycosylated. [UniProt] |
