ARG83742
Mouse Lymphotoxin Alpha / TNF beta ELISA Kit
Mouse Lymphotoxin Alpha / TNF beta ELISA Kit for ELISA and Mouse
Overview
| Product Description | ARG83742 Mouse Lymphotoxin Alpha / TNF beta ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse Lymphotoxin Alpha / TNF beta in serum and plasma (heparin, EDTA or citrate), cell culture supernatants |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | ELISA |
| Target Name | Lymphotoxin Alpha / TNF beta |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 10 pg/ml |
| Sample Type | serum and plasma (heparin, EDTA or citrate), cell culture supernatants |
| Standard Range | 62.5 pg/ml - 4000 pg/ml |
| Precision | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| Alternate Names | LTA; Lymphotoxin Alpha; TNFSF1; TNFB; LT; Tumor Necrosis Factor Ligand Superfamily Member 1; Lymphotoxin-Alpha; LT-Alpha; TNF-Beta; Lymphotoxin Alpha (TNF Superfamily, Member 1); Tumor Necrosis Factor Ligand 1E; Tumor Necrosis Factor Beta; TNF Superfamily, Member 1; TNF Superfamily Member 1; TNLG1E |
Application Instructions
| Assay Time | ~ 5 hours |
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Properties
| Form | 96 well |
|---|---|
| Storage Instruction | Store the kit at 4°C, -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | LTA |
|---|---|
| Gene Full Name | lymphotoxin alpha |
| Background | The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012] |
| Function | Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo. [UniProt] |
| Cellular Localization | Membrane; Secreted. [Uniprot] |
| PTM | Glycoprotein. [Uniprot] |
| Title | Download Link |
|---|---|
| ARG83742 Mouse Lymphotoxin Alpha TNF beta ELISA Kit-User manual 250613 |
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