ARG30230
Phospho Integrin beta 3 Antibody Panel (Total, pY773, pY785)
Cancer antibody; Cell Biology and Cellular Response antibody; Immune System antibody; Signaling Transduction antibody
Publication3
Component
| Cat No | Component Name | Host clonality | Reactivity | Application | Package |
|---|---|---|---|---|---|
| ARG51564 | anti-CD61 / Integrin beta 3 phospho (Tyr773) antibody | Rabbit pAb | Hu, Ms | IHC-P, WB | 50 μl |
| ARG51763 | anti-CD61 / Integrin beta 3 phospho (Tyr785) antibody | Rabbit pAb | Hu, Ms | WB | 50 μl |
| ARG54044 | anti-CD61 / Integrin beta 3 antibody (N-term) | Mouse mAb | Hu | WB | 50 μl |
| ARG65350 | Goat anti-Mouse IgG antibody (HRP) | Goat pAb | Ms | ELISA, IHC-P, WB | 50 μl |
| ARG65351 | Goat anti-Rabbit IgG antibody (HRP) | Goat pAb | Rb | ELISA, IHC-P, WB | 50 μl |
Overview
| Product Description | Cells recognize and respond to their extracellular environment through transmembrane receptors such as integrins, which physically connect the extracellular matrix to the cytoskeleton. Integrins provide the basis for the assembly of intracellular signaling platforms that link to the cytoskeleton and influence nearly every aspect of cell physiology. The integrin beta 3 protein mediates platelet adhesion to immobilized fibrinogen. Adhesion to fibrinogen induced rapid phosphorylation of Integrin beta 3 on Tyr773 and Tyr785 residues, which was reduced by Nitrogen Oxide in a cGMP independent manner. Oberprieler et al. 2007. FEBS Lett 581(7) Legate and Fassler. J Cell Sci 122: 187-98 |
|---|---|
| Target Name | Integrin beta 3 |
| Alternate Names | Phospho Integrin beta 3 antibody; CD61 / Integrin beta 3 phospho (Tyr773) antibody; CD61 / Integrin beta 3 phospho (Tyr785) antibody; CD61 / Integrin beta 3 antibody (N-term) |
Properties
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
|---|---|
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Full Name | Antibody Panel for Phospho Integrin beta 3 (Total, pY773, pY785) |
|---|---|
| Highlight | Related Product: anti-CD61 / Integrin beta 3 antibody; |
| Research Area | Cancer antibody; Cell Biology and Cellular Response antibody; Immune System antibody; Signaling Transduction antibody |
Images (8) Click the Picture to Zoom In
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ARG54044 anti-CD61 / Integrin beta 3 antibody (N-term) WB image
Western blot: 25 µg of Leukocyte lysate stained with ARG54044 anti-CD61 / Integrin beta 3 antibody (N-term) at 1:1000 dilution.
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ARG51564 anti-Integrin beta 3 phospho (Tyr773) antibody WB image
Western Blot: extracts from 293 cells stained with anti-Integrin beta 3 (phospho Tyr773) antibody ARG51564 and the same antibody preincubated with blocking peptide.
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ARG51564 anti-Integrin beta 3 phospho (Tyr773) antibody IHC-P image
Immunohistochemistry: paraffin-embedded human breast carcinoma tissue stained with anti-Integrin beta 3 (phospho Tyr773) antibody ARG51564 (left) or the same antibody preincubated with blocking peptide (right).
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ARG51763 anti-Integrin beta 3 phospho (Tyr785) antibody WB image
Western Blot: extracts from HUVEC cells stained with anti-Integrin beta 3 (phospho Tyr785) antibody ARG51763 and the same antibody preincubated with blocking peptide .
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ARG65350 Goat anti-Mouse IgG antibody (HRP) WB image
Western blot: Rat basolateral amygdala stained with ARG62347 anti-beta Tubulin antibody [BT7R] at 1:1000 dilution, ARG65350 Goat anti-Mouse IgG antibody (HRP) at 1:5000 dilution.
From Guang-Bing Duan et al. CNS Neurosci Ther. (2024), doi: 10.1111/cns.14611, Fig. 4.D.
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ARG65350 Goat anti-Mouse IgG antibody (HRP) IHC-P image
From Cheng-Feng Chu et al. J Pers Med. (2021), doi: 10.3390/jpm11121326, Fig. 6.
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ARG65351 Goat anti-Rabbit IgG antibody (HRP) WB image
Western blot: Mouse retina stained with ARG65693 anti-alpha Tubulin antibody and ARG65351 Goat anti-Rabbit IgG antibody (HRP)
From Xiaoyuan Ye et al. Mol Ther Nucleic Acids. (2024), doi: 10.1016/j.omtn.2024.102209, Fig. 5.D.
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ARG65351 Goat anti-Rabbit IgG antibody (HRP) IHC-P image
From Yu-Qian Song et al. J Mol Med (Berl) (2022), doi: 10.1007/s00109-021-02165-0, Fig. 5.c.
Specific References
Expression and correlation of Surfeit 4 gene in esophageal squamous cell carcinoma
ARG65350; WB /
Environmental acidification drives inter-organ energy mobilization to enhance reproductive performance in medaka (Oryzias latipes)
ARG65350; WB /
KDF1 Promoted Proliferation, Migration and Invasion of Lung Adenocarcinoma Cells through Activating STAT3 and AKT Pathway
ARG65350: WB /
