ARG82182
alpha Mannosidase Activity Assay Kit (Colorimetric)
alpha Mannosidase Activity Assay Kit (Colorimetric) for Functional study and Human,Mouse,Rat,All
Overview
| Product Description | ARG82182 alpha Mannosidase Activity Assay Kit (Colorimetric) can be used to measure alpha Mannosidase activity in serum, plasma, tissue and cell culture supernatants. |
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| Tested Reactivity | Hu, Ms, Rat, All |
| Tested Application | FuncSt |
| Target Name | alpha Mannosidase |
| Conjugation Note | Read at 405 nm |
| Sensitivity | 1 U/L |
| Detection Range | 1 - 250 U/L |
| Sample Type | serum, plasma, tissue and cell culture supernatants |
| Sample Volume | 10 µl |
| Alternate Names | Mannosidase alpha class 2A member 1; AMan II; Golgi alpha-mannosidase II; MANA2; Alpha-mannosidase 2; Man II; GOLIM7; Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase; MANII; EC 3.2.1.114 |
Application Instructions
| Application Note | Please note that this kit does not include a microplate. |
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| Assay Time | 10 min |
Properties
| Form | Liquid |
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| Storage Instruction | Store the kit at 2-8°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MAN2A1 |
| Gene Full Name | mannosidase, alpha, class 2A, member 1 |
| Background | This gene encodes a glycosyl hydrolase that localizes to the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus. [provided by RefSeq, Dec 2013] |
| Function | Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway. [UniProt] |
| Cellular Localization | Golgi apparatus membrane; Single-pass type II membrane protein. [UniProt] |
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| Title | Download Link |
|---|---|
| ARG82182 alpha Mannosidase Activity Assay Kit (Colorimetric) User manual |
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