ARG44070
anti-ABCC3 antibody
anti-ABCC3 antibody for Flow cytometry,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal recognizes ABCC3 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ABCC3 |
| Antigen Species | Human |
| Immunogen | Human ABCC3 recombinant protein (Position: H22-G1351). |
| Conjugation | Un-conjugated |
| Alternate Names | ABCC3; ATP Binding Cassette Subfamily C Member 3; CMOAT2; MOAT-D; MRP3; MLP2; Canalicular Multispecific Organic Anion Transporter 2; EST90757; ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3; ATP-Binding Cassette Sub-Family C Member 3; Multi-Specific Organic Anion Transporter D; Multidrug Resistance-Associated Protein 3; Canicular Multispecific Organic Anion Transporter; Multidrug Resistance Associated Protein; EC 3.6.3.44; EC 7.6.2.- ; EC 7.6.2.2; EC 7.6.2.3; EC 6.3.2.4; EC 3.6.3; ABC31 |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O15438 Human Canalicular multispecific organic anion transporter 2 |
|---|---|
| Gene Symbol | ABCC3 |
| Gene Full Name | ATP Binding Cassette Subfamily C Member 3 |
| Background | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. |
| Function | ATP-dependent transporter of the ATP-binding cassette (ABC) family that binds and hydrolyzes ATP to enable active transport of various substrates including many drugs, toxicants and endogenous compound across cell membranes. |
| Cellular Localization | Cell membrane, Membrane |
| Calculated MW | 169 kDa |
| PTM | Glycoprotein, Phosphoprotein |
Images (2) Click the Picture to Zoom In
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ARG44070 anti-ABCC3 antibody WB image
Western blot: HepG2 stained with ARG44070 anti-ABCC3 antibody at 0.5 μg/mL dilution.
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ARG44070 anti-ABCC3 antibody FACS image
Flow Cytometry: HepG2 stained with ARG44070 anti-ABCC3 antibody at 1 μg/1x10^6 cells dilution.
