ARG56484
anti-ACADM antibody
anti-ACADM antibody for Western blot and Human,Mouse,Pig,Sheep
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ACADM |
|---|---|
| Tested Reactivity | Hu, Ms, Pig, Sheep |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ACADM |
| Antigen Species | Human |
| Immunogen | Human recombinant MCAD. |
| Conjugation | Un-conjugated |
| Alternate Names | ACAD1; MCADH; EC 1.3.8.7; Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; MCAD |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | ACADM |
| Gene Full Name | acyl-CoA dehydrogenase, C-4 to C-12 straight chain |
| Background | This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Function | This enzyme is specific for acyl chain lengths of 4 to 16. [UniProt] |
| Calculated MW | 47 kDa |
| PTM | Acetylation at Lys-307 and Lys-311 in proximity of the cofactor-binding sites reduces catalytic activity (By similarity). These sites are deacetylated by SIRT3. |
