ARG10771
anti-ADCY5 antibody
anti-ADCY5 antibody for Confocal microscopy (Confocal),Dot blot,ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ADCY5 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | Confocal, Dot, ELISA, ICC/IF, IHC-P, IP, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ADCY5 |
| Antigen Species | Rat |
| Immunogen | Synthetic peptide from Rat ADCY5. |
| Conjugation | Un-conjugated |
| Alternate Names | FDFM; ATP pyrophosphate-lyase 5; AC5; Adenylate cyclase type V; Adenylate cyclase type 5; EC 4.6.1.1; Adenylyl cyclase 5 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 30% Glycerol and 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Adcy5 |
| Gene Full Name | adenylate cyclase 5 |
| Background | This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] |
| Function | This is a membrane-bound, calcium-inhibitable adenylyl cyclase. [UniProt] |
| Calculated MW | 139 kDa |
| PTM | Phosphorylated by RAF1. |
Images (2) Click the Picture to Zoom In
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ARG10771 anti-ADCY5 antibody ICC/IF image
Immunofluorescence: Rat striatal neurons stained with ARG10771 anti-ADCY5 antibody.
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ARG10771 anti-ADCY5 antibody WB image
Western blot: Recombinant ADCY5 protein stained with ARG10771 anti-ADCY5 antibody at 1:500 dilution.
