ARG64122
anti-ADH5 antibody
anti-ADH5 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Metabolism antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes ADH5 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Predict Reactivity | Cow, Dog, Pig |
| Tested Application | IHC-P, WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ADH5 |
| Antigen Species | Human |
| Immunogen | C-KKIKVDEFVTHN |
| Conjugation | Un-conjugated |
| Alternate Names | Glutathione-dependent formaldehyde dehydrogenase; hydroxymethyl; GSNOR; FDH; ADHX; EC 1.1.1.1; EC 1.1.1.-; Alcohol dehydrogenase class chi chain; GSH-FDH; S-; Alcohol dehydrogenase class-3; ADH-3; Alcohol dehydrogenase 5; FALDH; EC 1.1.1.284; Alcohol dehydrogenase class-III |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by antigen affinity chromatography. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq, Oct 2008] |
| Research Area | Metabolism antibody; Signaling Transduction antibody |
| Calculated MW | 40 kDa |
Images (1) Click the Picture to Zoom In
-
ARG64122 anti-ADH5 antibody WB image
Western Blot: Human Testis lysate (35 µg protein in RIPA buffer) stained with ARG64122 anti-ADH5 antibody at 0.5 µg/ml dilution.
