ARG41194
anti-AKAP7 antibody
anti-AKAP7 antibody for Western blot and Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes AKAP7 |
|---|---|
| Tested Reactivity | Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | AKAP7 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-81 of Human AKAP7 (NP_004833.1). |
| Conjugation | Un-conjugated |
| Alternate Names | AKAP15; AKAP-7 isoform gamma; A-kinase anchor protein 18 kDa; PRKA7 isoform gamma; A-kinase anchor protein 7 isoform gamma; Protein kinase A-anchoring protein 7 isoform gamma; AKAP 18; AKAP18 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Mouse brain | ||||
| Observed Size | 14 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O55074 Mouse A-kinase anchor protein 7 isoform alpha |
|---|---|
| Gene Symbol | AKAP7 |
| Gene Full Name | A kinase (PRKA) anchor protein 7 |
| Background | This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Apr 2011] |
| Function | Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium. [UniProt] |
| Cellular Localization | Nucleus. Cytoplasm. [UniProt] |
| Calculated MW | 40 kDa |
Images (1) Click the Picture to Zoom In
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ARG41194 anti-AKAP7 antibody WB image
Western blot: 25 µg of Mouse brain lysate stained with ARG41194 anti-AKAP7 antibody at 1:3000 dilution.
