ARG67238
anti-ALPK2 antibody
anti-ALPK2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ALPK2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ALPK2 |
| Conjugation | Un-conjugated |
| Alternate Names | ALPK2; Alpha Kinase 2; HAK; Heart Alpha-Protein Kinase; Alpha-Protein Kinase 2; Heart Alpha-Kinase; EC 2.7.11.1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 100 mM Tris Glycine (pH 7.0), 0.025% ProClin 300 and 20% Glycerol. |
| Preservative | 0.025% ProClin 300 |
| Stabilizer | 20% Glycerol |
| Concentration | 1.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | ALPK2 |
| Gene Full Name | Alpha Kinase 2 |
| Background | Predicted to enable ATP binding activity; histone H2AS1 kinase activity; and protein serine kinase activity. Involved in several processes, including epicardium morphogenesis; heart development; and negative regulation of Wnt signaling pathway involved in heart development. Acts upstream of or within regulation of gene expression. Located in basolateral plasma membrane. [provided by Alliance of Genome Resources, Nov 2024] |
| Function | Regulates cardiac development and cardiomyocyte differentiation by negatively regulating Wnt/beta-catenin signaling. [Uniprot] |
| Cellular Localization | Cell membrane, Membrane. [Uniprot] |
| Calculated MW | 237 kDa |
| PTM | Disulfide bond. [Uniprot] |
