ARG43651
anti-AP2 gamma antibody
anti-AP2 gamma antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes AP2 gamma |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | AP2 gamma |
| Antigen Species | Human |
| Immunogen | Synthetic peptide within a.a. 300-480 of Human AP2 gamma. |
| Conjugation | Un-conjugated |
| Protein Full Name | Transcription factor AP-2 gamma |
| Alternate Names | ERF1; TFAP2G; hAP-2g; Transcription factor ERF-1; Transcription factor AP-2 gamma; AP2-GAMMA; Activating enhancer-binding protein 2 gamma; AP2-gamma |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Rat lung | ||||
| Observed Size | ~50 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS, 0.01% Thiomersal and 50% Glycerol. |
| Preservative | 0.01% Thiomersal |
| Stabilizer | 50% Glycerol |
| Concentration | Batch dependent |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | TFAP2C |
| Gene Full Name | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| Background | The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube. [provided by RefSeq, Jul 2008] |
| Function | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. [UniProt] |
| Cellular Localization | Nucleus. |
| Calculated MW | 49 kDa |
| PTM | Sumoylated on Lys-10; which inhibits transcriptional activity. [UniProt] |
Images (1) Click the Picture to Zoom In
-
ARG43651 anti-AP2 gamma antibody WB image
Western blot: Mouse lung and HeLa cell stained with ARG43651 anti-AP2 gamma antibody WB image at 1:1000 dilution
