ARG66917
anti-APC15 antibody
anti-APC15 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes APC15 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | APC15 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to Human APC15. |
| Conjugation | Un-conjugated |
| Protein Full Name | Anaphase-promoting complex subunit 15 |
| Alternate Names | Anaphase-promoting complex subunit 15; HSPC020; C11orf51; APC15 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Jurkat | ||||
| Observed Size | 14 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Concentration | Batch dependent |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P60006 Human Anaphase-promoting complex subunit 15 |
|---|---|
| Gene Symbol | ANAPC15 |
| Gene Full Name | anaphase promoting complex subunit 15 |
| Function | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating in the responsiveness of the spindle assembly checkpoint. Also required for degradation of CDC20. [UniProt] |
| Cellular Localization | cytosol; nucleoplasm [UniProt] |
| Calculated MW | 14 kDa |
