ARG44776

anti-AREL1 antibody

anti-AREL1 antibody for Immunoprecipitation,Western blot and Human,Rat

Overview

Product Description Mouse Monoclonal antibody recognizes AREL1
Tested Reactivity Hu, Rat
Tested Application IP, WB
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Target Name AREL1
Antigen Species Human
Epitope FDIIVLSEDE KNIVERNVST SGVSIYFEAY LYNATNCSST PWHLPPMHMT SSQRRPSTAV DEEDEDSPSE CHTPEKVKKP
Conjugation Un-conjugated
Alternate Names AREL1; Apoptosis Resistant E3 Ubiquitin Protein Ligase 1; KIAA0317; FIEL1; Apoptosis-Resistant HECT-Type E3 Ubiquitin Transferase 1; Apoptosis-Resistant E3 Ubiquitin Protein Ligase 1; Fibrosis-Inducing E3 Ligase 1; EC 2.3.2.26

Application Instructions

Application Suggestion
Tested Application Dilution
IP1:100
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein A purification
Buffer PBS with 0.09% sodium azide
Preservative 0.09% sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 9870 Human AREL1

Swiss-port # O15033 Human Apoptosis-resistant E3 ubiquitin protein ligase 1

Gene Symbol AREL1
Gene Full Name Apoptosis Resistant E3 Ubiquitin Protein Ligase 1
Background Enables ubiquitin-protein transferase activity. Involved in negative regulation of apoptotic process; protein ubiquitination; and ubiquitin-dependent protein catabolic process. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
Function Modulates pulmonary inflammation by targeting SOCS2 for ubiquitination and subsequent degradation by the proteasome. [Uniprot]
PTM Ubl conjugation. [Uniprot]

Images (2) Click the Picture to Zoom In

  • ARG44776 anti-AREL1 antibody WB image

    Western blot: Rat brain stained with ARG44776 anti-AREL1 antibody at 1 µg/mL dilution.

  • ARG44776 anti-AREL1 antibody IP image

    Immunoprecipitation: Rat brain lysate immunoprecipitated with 2.5 µg of ARG44776 anti-AREL1 antibody.