ARG43271
anti-ARL8B antibody
anti-ARL8B antibody for ICC/IF,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ARL8B |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ARL8B |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 127-186 of Human ARL8B (NP_060654.1). |
| Conjugation | Un-conjugated |
| Alternate Names | Novel small G protein indispensable for equal chromosome segregation 1; ARL10C; ADP-ribosylation factor-like protein 8B; Gie1; ADP-ribosylation factor-like protein 10C |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | LO2 | ||||||
| Observed Size | ~ 22 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9CQW2 Mouse ADP-ribosylation factor-like protein 8B Swiss-port # Q9NVJ2 Human ADP-ribosylation factor-like protein 8B |
|---|---|
| Gene Symbol | ARL8B |
| Gene Full Name | ADP-ribosylation factor-like 8B |
| Function | Plays a role in lysosome motility (PubMed:16537643, PubMed:25898167). In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function (By similarity). May play a role in chromosome segregation (PubMed:15331635). [UniProt] |
| Cellular Localization | Late endosome membrane. Lysosome membrane. Cytoplasm, cytoskeleton, spindle. Note=Localizes with microtubules at the spindle mid-zone during mitosis. [UniProt] |
| Calculated MW | 22 kDa |
Images (2) Click the Picture to Zoom In
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ARG43271 anti-ARL8B antibody ICC/IF image
Immunofluorescence: U2OS cells stained with ARG43271 anti-ARL8B antibody at 1:100 dilution.
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ARG43271 anti-ARL8B antibody WB image
Western blot: 25 µg of LO2 cell lysate stained with ARG43271 anti-ARL8B antibody at 1:3000 dilution.
