ARG67228
anti-ASPM antibody
anti-ASPM antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ASPM |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Specificity | This antibody is specific to ASPM isoform1. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ASPM |
| Conjugation | Un-conjugated |
| Alternate Names | ASPM; Assembly Factor For Spindle Microtubules; Calmbp1; MCPH5; ASP; Abnormal Spindle-Like Microcephaly-Associated Protein; Abnormal Spindle Microtubule Assembly; FLJ10517; FLJ10549; Asp (Abnormal Spindle) Homolog, Microcephaly Associated (Drosophila); Asp (Abnormal Spindle)-Like, Microcephaly Associated (Drosophila); Asp (Abnormal Spindle) Homolog, Microcephaly Associated; Microcephaly, Primary Autosomal Recessive 5; Abnormal Spindle Protein Homolog; Asp Homolog |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 100 mM Tris Glycine (pH 7.0), 0.025% ProClin 300 and 20% Glycerol. |
| Preservative | 0.025% ProClin 300 |
| Stabilizer | 20% Glycerol |
| Concentration | 1.51 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8CJ27 Mouse Abnormal spindle-like microcephaly-associated protein homolog Swiss-port # Q8IZT6 Human Abnormal spindle-like microcephaly-associated protein |
|---|---|
| Gene Symbol | ASPM |
| Gene Full Name | Assembly Factor For Spindle Microtubules |
| Background | This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011] |
| Function | May have a preferential role in regulating neurogenesis. [Uniprot] |
| Cellular Localization | Cytoplasm, Cytoskeleton, Nucleus |
| Calculated MW | 410 kDa |
| PTM | Phosphoprotein |
