ARG20583
anti-Aquaporin 1 antibody
anti-Aquaporin 1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Aquaporin 1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Aquaporin 1 |
| Antigen Species | Rat |
| Immunogen | Synthetic peptide around the N-terminus of Rat Aquaporin 1. (N-MASEFKKKLF) |
| Conjugation | Un-conjugated |
| Alternate Names | AQP-1; Aquaporin-1; Water channel protein for red blood cells and kidney proximal tubule; CHIP28; Aquaporin-CHIP; CO; AQP-CHIP; Urine water channel |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.4), 0.09% Sodium azide and 50% Glycerol |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C . Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Aqp1 |
| Gene Full Name | aquaporin 1 |
| Background | Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This gene encodes an aquaporin which functions as a molecular water channel protein. It is a homotetramer with 6 bilayer spanning domains and N-glycosylation sites. The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance in ocular fluid movement. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] |
| Function | Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. [UniProt] |
| Calculated MW | 28.5 kDa (unmodified); 35 - 50 kDa (glycosylated) |
Images (2) Click the Picture to Zoom In
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ARG20583 anti-Aquaporin 1 antibody ICC/IF image
Immunofluorescence: Rat kidney tissue stained with ARG20583 anti-Aquaporin 1 antibody at 1:200 dilution. DAPI merge.
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ARG20583 anti-Aquaporin 1 antibody WB image
Western blot: Rat kidney tissue stained with ARG20583 anti-Aquaporin 1 antibody at 1:2000 dilution. Showing glyco and non-glycosylated bands.
