ARG44782
anti-BANK1 antibody
anti-BANK1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes BANK1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | BANK1 |
| Antigen Species | Human |
| Epitope | PGTMVEGQME RSQNWGHPGV RQETGDEPKG EKEKKEEEKE QEEEEDPYTF AEIDDSEYDM ILANLSIKKK TGSRSFIINR PPAPTPRPTS IPPKEETTPY IAQVFQQKTA RRQSDDDKFC GLPKKQDRAR IESPAFSTLR GCLTDGQEEL ILLQEKVKNG |
| Conjugation | Un-conjugated |
| Alternate Names | BANK1; B Cell Scaffold Protein With Ankyrin Repeats 1; BANK; B-Cell Scaffold Protein With Ankyrin Repeats; FLJ20706 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8NDB2 Human B-cell scaffold protein with ankyrin repeats |
|---|---|
| Gene Symbol | BANK1 |
| Gene Full Name | B Cell Scaffold Protein With Ankyrin Repeats 1 |
| Background | The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] |
| Function | Involved in B-cell receptor (BCR)-induced Ca2+ mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2. [Uniprot] |
| PTM | Phosphoprotein. [Uniprot] |
Images (2) Click the Picture to Zoom In
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ARG44782 anti-BANK1 antibody IHC-P image
Immunohistochemistry: Human tonsil stained with ARG44782 anti-BANK1 antibody at 5 µg/mL dilution.
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ARG44782 anti-BANK1 antibody WB image
Western blot: Raji stained with ARG44782 anti-BANK1 antibody at 1 µg/mL dilution.
