ARG55412
anti-BCAP31 / BAP31 antibody
anti-BCAP31 / BAP31 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
Cell Biology and Cellular Response antibody; Cell Death antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes BCAP31 / BAP31 |
|---|---|
| Tested Reactivity | Hu, Rat |
| Predict Reactivity | Ms |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | BCAP31 / BAP31 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide (17 aa) within the last 50 aa of Human BCAP31. |
| Conjugation | Un-conjugated |
| Alternate Names | BAP31; Bap31; 6C6-AG; DXS1357E; CDM; BCR-associated protein 31; 6C6-AG tumor-associated antigen; p28; Protein CDM; B-cell receptor-associated protein 31; DDCH |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Ramos Cell Lysate |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS and 0.02% Sodium azide |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P51572 Human B-cell receptor-associated protein 31 |
|---|---|
| Gene Symbol | BCAP31 |
| Gene Full Name | B-cell receptor-associated protein 31 |
| Background | This gene encodes a member of the B-cell receptor associated protein 31 superfamily. The encoded protein is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis. Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS), a neonatal disorder. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 16. [provided by RefSeq, Jan 2012] |
| Function | Functions as a chaperone protein. Is one of the most abundant endoplasmic reticulum (ER) proteins. Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD). Also serves as a cargo receptor for the export of transmembrane proteins. May be involved in CASP8-mediated apoptosis. [UniProt] |
| Research Area | Cell Biology and Cellular Response antibody; Cell Death antibody |
| Calculated MW | 28 kDa |
| PTM | Cleaved by CASP8 and other caspases. |
Images (2) Click the Picture to Zoom In
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ARG55412 anti-BCAP31 / BAP31 antibody WB image
Western blot: Ramos cell lysate stained with ARG55412 anti-BCAP31 / BAP31 antibody.
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ARG55412 anti-BCAP31 / BAP31 antibody IHC image
Immunohistochemistry: Rat lung tissue stained with ARG55412 anti-BCAP31 / BAP31 antibody at 2 µg/ml dilution.
