Overview

Product Description	Rabbit Polyclonal antibody recognizes BRWD1 / WDR9
Tested Reactivity	Hu, Ms
Tested Application	WB
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Target Name	BRWD1 / WDR9
Antigen Species	Human
Immunogen	Recombinant Protein of Human BRWD1 / WDR9.
Conjugation	Un-conjugated
Alternate Names	N143; WD repeat-containing protein 9; C21orf107; WDR9; Bromodomain and WD repeat-containing protein 1

Application Instructions

Application Suggestion	Tested Application Dilution WB 1:1000 - 1:3000
Application Note	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control	HeLa

Properties

Form	Liquid
Purification	Affinity purification with immunogen.
Buffer	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative	0.02% Sodium azide
Stabilizer	50% Glycerol
Storage Instruction	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 54014 Human BRWD1 GeneID: 93871 Mouse BRWD1 Swiss-port # Q921C3 Mouse Bromodomain and WD repeat-containing protein 1 Swiss-port # Q9NSI6 Human Bromodomain and WD repeat-containing protein 1
Gene Symbol	BRWD1
Gene Full Name	bromodomain and WD repeat domain containing 1
Background	This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.[provided by RefSeq, Jun 2011]
Function	May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. [UniProt]
Calculated MW	263 kDa

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