ARG24154
anti-Bassoon / BSN antibody (APC)
anti-Bassoon / BSN antibody (APC) for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | APC-conjugated Rabbit Polyclonal antibody recognizes Bassoon / BSN |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Specificity | Multiple isoforms can be detected. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Bassoon / BSN |
| Antigen Species | Human |
| Immunogen | His-tagged fusion protein |
| Conjugation | APC |
| Protein Full Name | Protein bassoon |
| Alternate Names | BSN; Bassoon Presynaptic Cytomatrix Protein; Zinc Finger Protein 231; ZNF231; Neuronal Double Zinc Finger Protein; Protein Bassoon; Bassoon (Presynaptic Cytomatrix Protein); KIAA0434 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G. |
| Buffer | PBS (pH 7.4), 50% Glycerol and 0.09% Sodium azide |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Full Name | Bassoon Presynaptic Cytomatrix Protein |
| Background | Neurotransmitters are released from a specific site in the axon terminal called the active zone, which is composed of synaptic vesicles and a meshwork of cytoskeleton underlying the plasma membrane. The protein encoded by this gene is thought to be a scaffolding protein involved in organizing the presynaptic cytoskeleton. The gene is expressed primarily in neurons in the brain. A similar gene product in rodents is concentrated in the active zone of axon terminals and tightly associated with cytoskeletal structures, and is essential for regulating neurotransmitter release from a subset of synapses. |
| Function | Scaffold protein of the presynaptic cytomatrix at the active zone (CAZ) which is the place in the synapse where neurotransmitter is released. |
| Cellular Localization | Cell projection, Cytoplasm, Cytoplasmic vesicle, Cytoskeleton, Membrane, Synapse |
| Calculated MW | 416 kDa |
| PTM | Glycoprotein, Lipoprotein, Methylation, Myristate, Phosphoprotein |
