ARG45193
anti-CACNA1S antibody
anti-CACNA1S antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat,Monkey
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CACNA1S |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Mk |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CACNA1S |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human CACNA1S. |
| Conjugation | Un-conjugated |
| Alternate Names | CACNA1S; Calcium Voltage-Gated Channel Subunit Alpha1 S; CACNL1A3; Cav1.1 ; HypoPP; Calcium Channel, Voltage-Dependent, L Type, Alpha 1S Subunit; Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1S; Voltage-Gated Calcium Channel Subunit Alpha Cav1.1; HOKPP; MHS5; Calcium Channel, L Type, Alpha-1 Polypeptide, Isoform, Skeletal Muscle; Dihydropyridine-Sensitive L-Type Calcium Channel Alpha-1 Subunit; Dihydropyridine Receptor Alpha 1 Subunit; CCHL1A3; CMYO18; CMYP18; HOKPP1; DHPRM; TTPP1; CACH1; CACN1 |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 220 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.005% Sodium azide and 4% Trehalose. |
| Preservative | 0.005% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q13698 Human Voltage-dependent L-type calcium channel subunit alpha-1S |
|---|---|
| Gene Symbol | CACNA1S |
| Gene Full Name | Calcium Voltage-Gated Channel Subunit Alpha1 S |
| Background | This gene encodes one of the five subunits of the slowly inactivating L-type voltage-dependent calcium channel in skeletal muscle cells. Mutations in this gene have been associated with hypokalemic periodic paralysis, thyrotoxic periodic paralysis and malignant hyperthermia susceptibility. [provided by RefSeq, Jul 2008] |
| Function | Pore-forming, alpha-1S subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle via their interaction with RYR1, which triggers Ca2+ release from the sarcoplasmic reticulum and ultimately results in muscle contraction. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group.. [UniProt] |
| Cellular Localization | Membrane; Cell membrane. [UniProt] |
| Calculated MW | 212 kDa |
| PTM | Disulfide bond; Glycoprotein; Phosphoprotein. [UniProt] |
