ARG45361
anti-CD119 / IFN gamma R antibody [7K23]
anti-CD119 / IFN gamma R antibody [7K23] for IHC-Formalin-fixed paraffin-embedded sections and Mouse
Overview
| Product Description | Rat Monoclonal antibody [7K23] recognizes CD119 / IFN gamma R |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | IHC-P |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | 7K23 |
| Isotype | IgG2 |
| Target Name | CD119 / IFN gamma R |
| Antigen Species | Mouse |
| Immunogen | Recombinant Mouse CD119 / IFN gamma R. |
| Conjugation | Un-conjugated |
| Alternate Names | Ifnz; BGIF; Lmtn; 6030405N23Rik; ENSMUSG00000073810 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | 54 kDa |
Properties
| Form | Powder |
|---|---|
| Purification | Protein G/A chromatography |
| Buffer | PBS |
| Reconstitution | PBS |
| Concentration | 0.2 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | IFNGR1 |
| Gene Full Name | interferon gamma receptor 1 |
| Background | This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008] |
| Function | Receptor for interferon gamma. Two receptors bind one interferon gamma dimer. [UniProt] |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein. [UniProt] |
| Calculated MW | 95 kDa |
| PTM | Phosphorylated at Ser/Thr residues. [UniProt] |
