ARG43870
anti-CD75 / ST6GAL1 antibody [LN1] (FITC)
anti-CD75 / ST6GAL1 antibody [LN1] (FITC) for Flow cytometry and Human
Overview
| Product Description | FITC-conjugated Mouse Monoclonal antibody recognize CD75 / ST6GAL1. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | LN1 |
| Isotype | IgM kappa |
| Target Name | CD75 / ST6GAL1 |
| Antigen Species | Human |
| Immunogen | Stimulated Human PBL |
| Conjugation | FITC |
| Alternate Names | SIAT1; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; B-cell antigen CD75; Sialyltransferase 1; ST6Gal I; Beta-galactoside alpha-2,6-sialyltransferase 1; EC 2.4.99.1; ST6N; Alpha 2,6-ST 1; ST6GalI |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified |
| Buffer | PBS (pH 7.4) and 15 mM Sodium azide |
| Preservative | 15 mM Sodium azide |
| Storage Instruction | Do not freeze. |
Bioinformation
| Database Links |
Swiss-port # P15907 Human Beta-galactoside alpha-2,6-sialyltransferase 1 |
|---|---|
| Gene Symbol | ST6GAL1 |
| Gene Full Name | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| Background | This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described. [provided by RefSeq, Aug 2009] |
| Function | Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates. [UniProt] |
| Cellular Localization | Golgi Apparatus; Golgi stack; Golgi stack membrane; single-pass type II membrane protein. Membrane-bound form in trans cisternae of Golgi. Secreted protein; body fluid. |
| Calculated MW | 47 kDa |
| PTM | The soluble form derives from the membrane form by proteolytic processing. The HB-6, CDW75, and CD76 differentiation antigens are cell-surface carbohydrate determinants generated by this enzyme. |
Images (1) Click the Picture to Zoom In
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ARG43870 anti-CD75 / ST6GAL1 antibody [LN1] (FITC) FACS image
Flow Cytometry: Human whole blood stained with ARG43870 anti-CD75 / ST6GAL1 antibody [LN1] (FITC) at 1:25 dilution.
