ARG45778
anti-CD89 antibody
anti-CD89 antibody for Flow cytometry,ICC/IF,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CD89 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CD89 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human CD89. |
| Conjugation | Un-conjugated |
| Alternate Names | FCAR; Fc fragment of IgA receptor; CD89; CTB-61M7.2; FcalphaRI; CD antigen CD89; Immunoglobulin alpha Fc receptor; IgA Fc receptor |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 32 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | FCAR |
| Gene Full Name | Fc fragment of IgA receptor |
| Background | This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
| Function | Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. [UniProt] |
| Cellular Localization | Isoform A.1: Cell membrane; Single-pass type I membrane protein. Isoform A.2: Cell membrane; Single-pass type I membrane protein. Isoform A.3: Cell membrane; Single-pass type I membrane protein. Isoform B: Secreted. Isoform B-delta-S2: Secreted. [. [UniProt] |
| Calculated MW | 32 kDa |
| PTM | Disulfide bond; Glycoprotein. [UniProt] |
