ARG44597
anti-CD97 antibody [MEM-180] (PE)
anti-CD97 antibody [MEM-180] (PE) for Flow cytometry and Human
Developmental Biology antibody; Immune System antibody; Neuroscience antibody; Signaling Transduction antibody
Overview
| Product Description | PE-conjugated Mouse Monoclonal antibody recognizes CD97 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | MEM-180 |
| Isotype | IgG1 |
| Target Name | CD97 |
| Antigen Species | Human |
| Conjugation | PE |
| Alternate Names | ADGRE5; Adhesion G Protein-Coupled Receptor E5; Leukocyte Antigen CD97; TM7LN1; CD97; Seven-Transmembrane, Heterodimeric Receptor Associated With Inflammation; Seven Transmembrane Helix Receptor; Seven-Span Transmembrane Protein; CD97 Molecule; CD97 Antigen |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified antibody is conjugated with R-phycoerythrin (PE), and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
| Buffer | PBS (pH 7.4) and 15 mM Sodium azide |
| Preservative | 15 mM Sodium azide |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | ADGRE5 |
| Gene Full Name | adhesion G protein-coupled receptor E5 |
| Background | This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011] |
| Function | Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration. [UniProt] |
| Cellular Localization | Cell membrane, Membrane, Secreted. [UniProt] |
| Research Area | Developmental Biology antibody; Immune System antibody; Neuroscience antibody; Signaling Transduction antibody |
| Calculated MW | 92 kDa |
| PTM | Disulfide bond, Glycoprotein, Phosphoprotein. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG44597 anti-CD97 antibody [MEM-180] (PE) FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG44597 anti-CD97 antibody [MEM-180] (PE) at 10 μl/ 100 μl dilution.
