Overview

Product Description	Rabbit Polyclonal antibody recognizes CDCA3
Tested Reactivity	Hu
Predict Reactivity	Ms, Rat
Tested Application	ICC/IF, WB
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Target Name	CDCA3
Antigen Species	Human
Immunogen	Synthetic peptide of Human CDCA3.
Conjugation	Un-conjugated
Alternate Names	Cell division cycle-associated protein 3; Gene-rich cluster protein C8; Trigger of mitotic entry protein 1; TOME-1; GRCC8

Application Instructions

Application Suggestion	Tested Application Dilution ICC/IF 1:50 - 1:100 WB 1:500 - 1:1000
Application Note	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control	MCF7
Observed Size	~ 27 kDa

Properties

Form	Liquid
Purification	Affinity purified.
Buffer	PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
Preservative	0.02% Sodium azide
Stabilizer	50% Glycerol
Storage Instruction	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 83461 Human CDCA3 Swiss-port # Q99618 Human Cell division cycle-associated protein 3
Gene Symbol	CDCA3
Gene Full Name	cell division cycle associated 3
Function	F-box-like protein which is required for entry into mitosis. Acts by participating in E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase (By similarity). [UniProt]
Cellular Localization	Cytoplasm, cytosol. [UniProt]
Calculated MW	29 kDa
PTM	Ubiquitinated and degraded by the APC/C-Cdh1 complex. [UniProt]

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