ARG58892
anti-CDY1 + CDY2A antibody
anti-CDY1 + CDY2A antibody for Western blot and Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CDY1 + CDY2A |
|---|---|
| Tested Reactivity | Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CDY1 + CDY2A |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 60-320 of Human CDY1B (NP_001003895.1). |
| Conjugation | Un-conjugated |
| Alternate Names | EC 2.3.1.48; CDY; Testis-specific chromodomain protein Y 1 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Mouse testis | ||||
| Observed Size | 68 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | CDY1B |
|---|---|
| Gene Full Name | chromodomain protein, Y-linked, 1B |
| Background | This gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. The human chromosome Y has two identical copies of this gene within a palindromic region; this record represents the more centromeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. Two protein isoforms are encoded by transcript variants of this gene. Additional transcript variants have been described, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008] |
| Function | Has histone acetyltransferase activity, with a preference for histone H4. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 60 kDa |
Images (1) Click the Picture to Zoom In
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ARG58892 anti-CDY1 + CDY2A antibody WB image
Western blot: 25 µg of Mouse testis lysate stained with ARG58892 anti-CDY1 + CDY2A antibody at 1:1000 dilution.
