ARG45963

anti-CLCN2 antibody

anti-CLCN2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Neuroscience antibody; Signaling Transduction antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes CLCN2
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CLCN2
Antigen Species Human
Immunogen Synthesize peptide from human CLCN2, corresponding to amino acid residues L835-P885.
Conjugation Un-conjugated
Alternate Names EGI3; Chloride channel protein 2; ClC-2; clC-2; EGI11; CLC2; LKPAT; EJM6; ECA3; ECA2; EGMA; CIC-2; EJM8

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:100-1:500
IHC-P1:50 - 1:200
WB1:1000 - 1:3000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1181 Human CLCN2

GeneID: 12724 Mouse CLCN2

GeneID: 29232 Rat CLCN2

Background This gene encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
Research Area Neuroscience antibody; Signaling Transduction antibody
Calculated MW 99 kDa
PTM Phosphorylated. Activated by dephosphorylation.