ARG58385
anti-CPE / Carboxypeptidase E antibody
anti-CPE / Carboxypeptidase E antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CPE / Carboxypeptidase E |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CPE / Carboxypeptidase E |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 257-476 of Human CPE / Carboxypeptidase E (NP_001864.1). |
| Conjugation | Un-conjugated |
| Alternate Names | CPH; Carboxypeptidase H; Enkephalin convertase; CPE; Carboxypeptidase E; Prohormone-processing carboxypeptidase; EC 3.4.17.10 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | A549 | ||||
| Observed Size | 55 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CPE |
| Gene Full Name | carboxypeptidase E |
| Background | This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes. [provided by RefSeq, Jul 2008] |
| Function | Removes residual C-terminal Arg or Lys remaining after initial endoprotease cleavage during prohormone processing. Processes proinsulin. [UniProt] |
| Cellular Localization | Cytoplasmic vesicle, secretory vesicle membrane, Peripheral membrane protein, Secreted, Nucleus. [UniProt] |
| Calculated MW | 53 kDa |
Images (1) Click the Picture to Zoom In
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ARG58385 anti-CPE / Carboxypeptidase E antibody WB image
Western blot: 25 µg of A549 cell lysate stained with ARG58385 anti-CPE / Carboxypeptidase E antibody at 1:1000 dilution.
