ARG56615
anti-CXCL10 / IP10 antibody
anti-CXCL10 / IP10 antibody for ELISA,IHC-Frozen sections,Neutralizing,Western blot and Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CXCL10 / IP10 |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | ELISA, IHC-Fr, Neut, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CXCL10 / IP10 |
| Antigen Species | Mouse |
| Immunogen | E.coli derived Recombinant Mouse IP-10 (CXCL10). (IPLARTVRCN CIHIDDGPVR MRAIGKLEII PASLSCPRVE IIATMKKNDE QRCLNPESKT IKNLMKAFSQ KRSKRAP) |
| Conjugation | Un-conjugated |
| Alternate Names | gIP-10; INP10; 10 kDa interferon gamma-induced protein; IP-10; C-X-C motif chemokine 10; 1-73; Small-inducible cytokine B10; IFI10; Gamma-IP10; SCYB10; crg-2; C7; mob-1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.2) |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Cxcl10 |
| Gene Full Name | chemokine (C-X-C motif) ligand 10 |
| Background | This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. [provided by RefSeq, Sep 2014] |
| Function | Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3. [UniProt] |
| Highlight | Related products: CXCL10 antibodies; CXCL10 ELISA Kits; CXCL10 recombinant proteins; Anti-Rabbit IgG secondary antibodies; Related news: circNDUFB2, a circular RNA (circRNA), activates anti-tumor immunity |
| Calculated MW | 11 kDa |
| PTM | CXCL10(1-73) is produced by proteolytic cleavage after secretion from keratinocytes. |
Images (5) Click the Picture to Zoom In
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ARG56615 anti-CXCL10 / IP10 antibody IHC-Fr image
Immunohistochemistry: Frozen section of Colchicine injected Mouse brain (including the hippocampus region) tissue stained with ARG56615 anti-CXCL10 / IP10 antibody at 1.0 µg/ml, overnight at 4˚C. This was followed by a peroxidase conjugated secondary antibody and then a fluorescein Tyramide Signal Amplification (TSA™) reagent.
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ARG56615 anti-CXCL10 / IP10 antibody WB image
Western blot: 250 - 0.24 ng of Mouse IP-10 stained with ARG56615 anti-CXCL10 / IP10 antibody, under reducing conditions.
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ARG56615 anti-CXCL10 / IP10 antibody IHC-Fr image
Immunohistochemistry: Frozen section of Colchicine injected Mouse brain (including the hippocampus region) tissue stained with ARG56615 anti-CXCL10 / IP10 antibody at 1.0 µg/ml, overnight at 4˚C. This was followed by a peroxidase conjugated secondary antibody and then a fluorescein Tyramide Signal Amplification (TSA™) reagent.
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ARG56615 anti-CXCL10 / IP10 antibody WB image
Western blot: 250 - 0.24 ng of Mouse IP-10 stained with ARG56615 anti-CXCL10 / IP10 antibody, under non-reducing conditions.
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ARG56615 anti-CXCL10 / IP10 antibody standard curve image
Sandwich ELISA: ARG56615 anti-CXCL10 / IP10 antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG56729 anti-CXCL10 / IP10 antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density.
