ARG67030
anti-CXCR5 antibody [SQab30323]
anti-CXCR5 antibody [SQab30323] for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Recombinant rabbit Monoclonal antibody [SQab30323] recognizes CXCR5 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | SQab30323 |
| Isotype | IgG |
| Target Name | CXCR5 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide of Human CXCR5. |
| Conjugation | Un-conjugated |
| Protein Full Name | C-X-C chemokine receptor type 5 |
| Alternate Names | CXCR5, C-X-C Motif Chemokine Receptor 5, MDR15, CD185, BLR1, Burkitt Lymphoma Receptor 1, GTP Binding Protein (Chemokine (C-X-C Motif) Receptor 5), Burkitt Lymphoma Receptor 1, GTP-Binding Protein, Chemokine (C-X-C Motif) Receptor 5, C-X-C Chemokine Receptor Type 5, Monocyte-Derived Receptor 15, CXC-R5, CXCR-5, MDR-15, Burkitt Lymphoma Receptor 1, CD185 Antigen |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Human tonsil |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 40% Glycerol and 0.05%BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CXCR5 |
| Gene Full Name | C-X-C Motif Chemokine Receptor 5 |
| Background | This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] |
| Function | Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. [Uniprot] |
| Cellular Localization | Cell membrane, Membrane |
| Calculated MW | 42 kDa |
| PTM | Disulfide bond, Glycoprotein |
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