ARG59478
anti-Collagen X antibody
anti-Collagen X antibody for ICC/IF,Western blot and Human,Mouse,Pig,Rat
Publication3
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Collagen X |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Pig |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Collagen X |
| Antigen Species | Human |
| Immunogen | Synthetic peptide of Human Collagen X. |
| Conjugation | Un-conjugated |
| Alternate Names | Collagen alpha-1(X) chain |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | COL10A1 |
| Gene Full Name | collagen, type X, alpha 1 |
| Background | This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD). [provided by RefSeq, Jul 2008] |
| Function | Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage. [UniProt] |
| Cellular Localization | Secreted, extracellular space, extracellular matrix. [UniProt] |
| Calculated MW | 66 kDa |
| PTM | Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG59478 anti-Collagen X antibody ICC/IF image
Immunofluorescence: Human articular chondrocytes stained with ARG20787 anti-Collagen II antibody, pre-adsorbed and ARG59478 anti-Collagen X antibody.
From Yuxuan Zhang et al. Comput Math Methods Med (2022), doi: 10.1155/2022/8388473, Fig. 3 (e) (f) (g).
Specific References
Nanohydroxyapatite Hydrogel Can Promote the Proliferation and Migration of Chondrocytes and Better Repair Talar Articular Cartilage
ICC/IF / Mouse
Suramin attenuates intervertebral disc degeneration by inhibiting NF-κB signalling pathway
WB / Pig
Shockwave Treatment Enhances the Extracellular Matrix Production in Articular Chondrocyte Through Activation of the ROS/MAPK/Nrf2 Signaling Pathway.
WB / Pig
