ARG24005
anti-Collagen XI antibody
anti-Collagen XI antibody for ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and Bovine
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Collagen XI |
|---|---|
| Tested Reactivity | Bov |
| Tested Application | ELISA, ICC/IF, IHC-P |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Collagen XI |
| Antigen Species | Bovine |
| Immunogen | Type XI collagen extracted from Bovine cartilage. |
| Conjugation | Un-conjugated |
| Alternate Names | STL2; COLL6; CO11A1; Collagen alpha-1(XI) chain |
Application Instructions
| Application Suggestion |
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| Application Note | IHC-P: Antigen Retrieval: treat sections with 0.5% hyaluronidase at RT for 1hr before staining. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified. |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | COL11A1 |
|---|---|
| Gene Full Name | collagen, type XI, alpha 1 |
| Background | This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009] |
| Function | May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils. [UniProt] |
| Cellular Localization | Secreted, extracellular space, extracellular matrix. [UniProt] |
| Calculated MW | 181 kDa |
| PTM | Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. N-glycosylated. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG24005 anti-Collagen XI antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Bovine cartilage tissue stained with ARG24005 anti-Collagen XI antibody.
