ARG45814
anti-DBF4 antibody
anti-DBF4 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes DBF4 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | DBF4 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human DBF4. |
| Conjugation | Un-conjugated |
| Alternate Names | DBF4; DBF4-CDC7 Kinase Regulatory Subunit; ZDBF1; DBF4A; ASK; Activator Of S Phase Kinase; Chif; DBF4-Type Zinc Finger-Containing Protein 1; Zinc Finger, DBF-Type Containing 1; Regulatory Subunit Of DDK; Protein DBF4 Homolog A; DBF4 Zinc Finger A; Chiffon Homolog A; Chiffon Homolog (Drosophila); DBF4 Homolog (S. Cerevisiae); DBF4 Zinc Finger; DBF4 Homolog |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 80 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | DBF4 |
| Gene Full Name | DBF4-CDC7 Kinase Regulatory Subunit |
| Background | Predicted to enable protein serine/threonine kinase activator activity. Predicted to be involved in positive regulation of nuclear cell cycle DNA replication and regulation of cell cycle phase transition. Located in nuclear body. [provided by Alliance of Genome Resources, Feb 2025] |
| Function | Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 77 kDa |
| PTM | Phosphoprotein. [UniProt] |
