ARG45632

anti-DIAPH1 antibody

anti-DIAPH1 antibody for Flow cytometry,ICC/IF,Western blot and Human,Monkey

Overview

Product Description Rabbit Polyclonal antibody recognizes DIAPH1
Tested Reactivity Hu, Mk
Tested Application FACS, ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name DIAPH1
Antigen Species Human
Immunogen Recombinant protein containing to human DIAPH1.
Conjugation Un-conjugated
Alternate Names DIAPH1; Diaphanous Related Formin 1; HDIA1; LFHL1; MDia1; Mammalian Diaphanous Related Formin 1; Protein Diaphanous Homolog 1; DFNA1; DRF1; Diaphanous (Drosophila, Homolog) 1; Diaphanous Homolog 1 (Drosophila); Diaphanous-Related Formin-1; SCBMS; DIAP1; DIA1

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1 - 3 µg/10^6 cells
ICC/IF5 μg/ml
WB0.25-0.5 μg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purified
Buffer 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
Stabilizer 4% Trehalose
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1729 Human DIAPH1

Swiss-port # O60610 Human Protein diaphanous homolog 1

Gene Symbol DIAPH1
Gene Full Name Diaphanous Related Formin 1
Background This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function Actin nucleation and elongation factor required for the assembly of F-actin structures, such as actin cables and stress fibers (By similarity). [UniProt]
Cellular Localization Cell membrane; Cell projection; Cytoplasm; Cytoskeleton; Membrane; Nucleus. [UniProt]
Calculated MW 141 kDa
PTM Acetylation; Phosphoprotein. [UniProt]