ARG58499
anti-DIAPH2 antibody
anti-DIAPH2 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes DIAPH2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | DIAPH2 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-120 of Human DIAPH2 (NP_009293.1). |
| Conjugation | Un-conjugated |
| Alternate Names | Diaphanous-related formin-2; DRF2; Protein diaphanous homolog 2; POF2; DIA; POF; DIA2 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | H460 | ||||
| Observed Size | 135 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | DIAPH2 |
| Gene Full Name | diaphanous-related formin 2 |
| Background | The product of this gene belongs to the diaphanous subfamily of the formin homology family of proteins. This gene may play a role in the development and normal function of the ovaries. Defects in this gene have been linked to premature ovarian failure 2. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| Function | Could be involved in oogenesis. Involved in the regulation of endosome dynamics. Implicated in a novel signal transduction pathway, in which isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton. [UniProt] |
| Cellular Localization | Cytoplasm, cytosol, Early endosome. [UniProt] |
| Calculated MW | 126 kDa |
Images (1) Click the Picture to Zoom In
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ARG58499 anti-DIAPH2 antibody WB image
Western blot: 25 µg of H460 cell lysate stained with ARG58499 anti-DIAPH2 antibody at 1:1000 dilution.
