ARG45952
anti-DNA polymerase mu antibody
anti-DNA polymerase mu antibody for Western blot,Immunoprecipitation and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes DNA polymerase mu |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IP, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | DNA polymerase mu |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human DNA polymerase mu. |
| Conjugation | Un-conjugated |
| Alternate Names | DNA Polymerase Mu; POLM; polmu; DNA-directed DNA/RNA polymerase mu; Pol Mu; EC 2.7.7.7; Terminal transferase |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 55 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9NP87 Human DNA-directed DNA/RNA polymerase mu |
|---|---|
| Gene Symbol | POLM |
| Gene Full Name | DNA Polymerase Mu |
| Background | Predicted to enable DNA-directed DNA polymerase activity. Predicted to be involved in double-strand break repair via nonhomologous end joining. Predicted to act upstream of or within B cell differentiation and somatic hypermutation of immunoglobulin genes. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, May 2025] |
| Function | Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 55 kDa |
| PTM | Phosphoprotein. [UniProt]. [UniProt] |
