ARG43023
anti-DNAJA2 antibody
anti-DNAJA2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes DNAJA2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | DNAJA2 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 233-412 of Human DNAJA2 (NP_005871.1). |
| Conjugation | Un-conjugated |
| Alternate Names | Dnj3; DJ3; Dj3; Cell cycle progression restoration gene 3 protein; DnaJ homolog subfamily A member 2; PRO3015; RDJ2; DJA2; HIRA-interacting protein 4; DNJ3; HIRIP4; DNAJ; CPR3; Renal carcinoma antigen NY-REN-14 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | MCF7 |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | DNAJA2 |
| Gene Full Name | DnaJ (Hsp40) homolog, subfamily A, member 2 |
| Background | The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro. [provided by RefSeq, Jul 2008] |
| Function | Co-chaperone of Hsc70. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro) (PubMed:24318877). [UniProt] |
| Cellular Localization | Membrane; Lipid-anchor. [UniProt] |
| Calculated MW | 46 kDa |
Images (2) Click the Picture to Zoom In
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ARG43023 anti-DNAJA2 antibody ICC/IF image
Immunofluorescence: NIH/3T3 cells stained with ARG43023 anti-DNAJA2 antibody at 1:100 dilution.
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ARG43023 anti-DNAJA2 antibody WB image
Western blot: 25 µg of MCF7 cell lysate stained with ARG43023 anti-DNAJA2 antibody at 1:3000 dilution.
