ARG56480
anti-DP1 Receptor antibody
anti-DP1 Receptor antibody for ICC/IF,Western blot and Human,Mouse,Rat
Publication1
Overview
| Product Description | Rabbit Polyclonal antibody recognizes DP1 Receptor |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | DP1 Receptor |
| Antigen Species | Mouse |
| Immunogen | Synthetic peptide around the N-terminus of Mouse DP1 Receptor. |
| Conjugation | Un-conjugated |
| Alternate Names | PTGDR1; AS1; DP1; ASRT1; PGD receptor; Prostanoid DP receptor; Prostaglandin D2 receptor; DP; PGD2 receptor |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | TBS (pH 7.4), 0.02% Sodium azide, 50% Glycerol and 0.1% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.1% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Ptgdr |
| Gene Full Name | prostaglandin D receptor |
| Background | This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein is reported to be a receptor for prostaglandin D2, which is a mediator of allergic inflammation and allergic airway inflammation in asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| Function | Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity). [UniProt] |
| Calculated MW | 40 kDa |
Images (1) Click the Picture to Zoom In
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ARG56480 anti-DP1 Receptor antibody WB image
Western blot: 1) Precision Plus Protein Standard, 2) 10 µg of HT-29 cell lysate, 3) 20 µg of HT-29 cell lysate, and 4) 40 µg of HT-29 cell lysate stained with ARG56480 anti-DP1 Receptor antibody.
Specific References
L-PGDS–PGD2–DP1 Axis Regulates Phagocytosis by CD36+ MGs/MΦs That Are Exclusively PresentWithin Ischemic Areas After Stroke
IHC-P / Mouse
