ARG45151
anti-EAG1 antibody
anti-EAG1 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes EAG1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | EAG1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human EAG1. |
| Conjugation | Un-conjugated |
| Alternate Names | KCNH1; potassium voltage-gated channel subfamily H member 1; H-Eag; K(V)10.1; Kv10.1; Eag1; HEAG; EagPotassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 1; Voltage-Gated Delayed Rectifier Potassium Channel KCNH1; Voltage-Gated Potassium Channel Subunit Kv10.1; Ether-A-Go-Go Potassium Channel 1; Ether-A-Go-Go 1; EAG Channel 1; HEAG1; Potassium Channel, Voltage Gated Eag Related Subfamily H, Member 1; Ether-A-Go-Go, Drosophila, Homolog Of; TMBTS; ZLS1 |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 160 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | KCNH1 |
| Gene Full Name | potassium voltage-gated channel subfamily H member 1 |
| Background | Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
| Function | Pore-forming (alpha) subunit of a voltage-gated delayed rectifier potassium channel that mediates outward-rectifying potassium currents which, on depolarization, reaches a steady-state level and do not inactivate. [UniProt] |
| Cellular Localization | Nucleus inner membrane; Cell projection, dendrite; Cell projection, axon; Presynaptic cell membrane; Perikaryon; Postsynaptic density membrane; Early endosome membrane. [UniProt] |
| Calculated MW | 111 kDa |
| PTM | Glycoprotein; Phosphoprotein. [UniProt] |
