ARG45822
anti-ELOVL4 antibody
anti-ELOVL4 antibody for Flow cytometry,ICC/IF,Western blot and Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ELOVL4 |
|---|---|
| Tested Reactivity | Ms, Rat |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ELOVL4 |
| Antigen Species | Mouse |
| Immunogen | Recombinant protein containing to mouse ELOVL4. |
| Conjugation | Un-conjugated |
| Alternate Names | ELOVL4; ELOVL Fatty Acid Elongase 4; CT118; Elongation Of Very Long Chain Fatty Acids (FEN1/Elo2, SUR4/Elo3, Yeast)-Like 4; Elongation Of Very Long Chain Fatty Acids Protein 4; Very Long Chain 3-Ketoacyl-CoA Synthase 4; Very Long Chain 3-Oxoacyl-CoA Synthase 4; Very Long Chain Fatty Acid Elongase 4; 3-Keto Acyl-CoA Synthase ELOVL4; Cancer/Testis Antigen 118; ELOVL FA Elongase 4; SCA34; STGD2; STGD3; Spinocerebellar Ataxia 34; EC 2.3.1.199; ISQMR; ADMD |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 37 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | Elovl4 |
|---|---|
| Gene Full Name | ELOVL Fatty Acid Elongase 4 |
| Background | This gene encodes a membrane-bound protein which is a member of the ELO family, proteins which participate in the biosynthesis of fatty acids. Consistent with the expression of the encoded protein in photoreceptor cells of the retina, mutations and small deletions in this gene are associated with Stargardt-like macular dystrophy (STGD3) and autosomal dominant Stargardt-like macular dystrophy (ADMD), also referred to as autosomal dominant atrophic macular degeneration. [provided by RefSeq, Jul 2008] |
| Function | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of very long chain saturated (VLC-SFA) and polyunsaturated (PUFA) fatty acids that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May play a critical role in early brain and skin development. [UniProt] |
| Cellular Localization | Endoplasmic reticulum; Membrane. [UniProt] |
| Calculated MW | 37 kDa |
| PTM | Glycoprotein. [UniProt] |
