ARG45382
anti-EMILIN1 antibody [1H2/G8]
anti-EMILIN1 antibody [1H2/G8] for ICC/IF,IHC-Frozen sections,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [1H2/G8] recognizes EMILIN1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, IHC-Fr, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1H2/G8 |
| Isotype | IgG2a |
| Target Name | EMILIN1 |
| Antigen Species | Human |
| Immunogen | Recombinant Human EMILIN1. |
| Conjugation | Un-conjugated |
| Alternate Names | EMILIN1; Elastin Microfibril Interfacer 1; EMILIN; Gp115; Elastin Microfibril Interface-Located Protein 1; DKFZp586M121; EMILIN-1; EMI; HMND10; ATBFS; HMN10 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein-G purified |
| Buffer | PBS |
| Concentration | 0.1 - 1.0 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | EMILIN1 |
| Gene Full Name | Elastin Microfibril Interfacer 1 |
| Background | This gene encodes an extracellular matrix glycoprotein that is characterized by an N-terminal microfibril interface domain, a coiled-coiled alpha-helical domain, a collagenous domain and a C-terminal globular C1q domain. The encoded protein associates with elastic fibers at the interface between elastin and microfibrils and may play a role in the development of elastic tissues including large blood vessels, dermis, heart and lung. [provided by RefSeq, Sep 2009] |
| Function | Involved in elastic and collagen fibers formation. It is required for EFEMP2 deposition into the extracellular matrix, and collagen network assembly and cross-linking via protein-lysine 6-oxidase/LOX activity (PubMed:36351433)._x000D_ May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved in the processes that regulate vessel assembly. Has cell adhesive capacity. [UniProt] |
| Cellular Localization | Extracellular matrix; Secreted. [UniProt] |
| Calculated MW | 107 kDa |
| PTM | Disulfide bond; Glycoprotein. [UniProt] |
