ARG45248
anti-EPLIN antibody
anti-EPLIN antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Polyclonal antibody recognizes EPLIN |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | EPLIN |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human EPLIN. |
| Conjugation | Un-conjugated |
| Alternate Names | LIMA1; LIM Domain And Actin Binding 1; EPLIN; Epithelial Protein Lost In Neoplasm Beta; LIM Domain And Actin-Binding Protein 1; SREBP3; Sterol Regulatory Element Binding Protein 3; Epithelial Protein Lost In Neoplasm; LDLCQ8 |
Application Instructions
| Application Suggestion |
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 85 kDa; 100 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9UHB6 Human LIM domain and actin-binding protein 1 |
|---|---|
| Gene Symbol | LIMA1 |
| Gene Full Name | LIM Domain And Actin Binding 1 |
| Background | This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated. [provided by RefSeq, Aug 2011]. |
| Function | Actin-binding protein involved in actin cytoskeleton regulation and dynamics. Increases the number and size of actin stress fibers and inhibits membrane ruffling. Inhibits actin filament depolymerization. Bundles actin filaments, delays filament nucleation and reduces formation of branched filaments. [UniProt] |
| Cellular Localization | Cell junction ; Cell membrane ; Cell projection ; Cytoplasm ; Cytoskeleton ; Membrane. [UniProt] |
| Calculated MW | 85 kDa |
| PTM | Acetylation ; Phosphoprotein. [UniProt] |
