ARG67210
anti-Endocan antibody
anti-Endocan antibody for IHC-Frozen sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Endocan |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-Fr, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target Name | Endocan |
| Antigen Species | Human |
| Immunogen | Recombinant protein corresponding to Human Endocan (a.a. sequence W19-R184). |
| Conjugation | Un-conjugated |
| Alternate Names | ESM1; Endothelial Cell Specific Molecule 1; Endothelial Cell-Specific Molecule 1; ESM-1; Endocan |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purified |
| Buffer | 0.5X PBS, pH 7.2 |
| Concentration | 0.1 - 1.0 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9NQ30 Human Endothelial cell-specific molecule 1 |
|---|---|
| Gene Symbol | ESM1 |
| Gene Full Name | Endothelial Cell Specific Molecule 1 |
| Background | This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] |
| Function | Involved in angiogenesis; promotes angiogenic sprouting. May have potent implications in lung endothelial cell-leukocyte interactions. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 20 kDa |
| PTM | Disulfide bond; Glycoprotein; Proteoglycan. [UniProt] |
