ARG40065
anti-FA2H antibody
anti-FA2H antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes FA2H |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | FA2H |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 95-170 of Human FA2H (NP_077282.3). |
| Conjugation | Un-conjugated |
| Alternate Names | SCS7; SPG35; FAH1; Fatty acid 2-hydroxylase; Fatty acid alpha-hydroxylase; EC 1.-.-.-; FAXDC1; FAAH |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | HT-29 | ||||
| Observed Size | 38 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | FA2H |
| Gene Full Name | fatty acid 2-hydroxylase |
| Background | This gene encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups. Mutations in this gene have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia.[provided by RefSeq, Mar 2010] |
| Function | Required for alpha-hydroxylation of free fatty acids and the formation of alpha-hydroxylated sphingolipids. [UniProt] |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein. [UniProt] |
| Calculated MW | 43 kDa |
Images (1) Click the Picture to Zoom In
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ARG40065 anti-FA2H antibody WB image
Western blot: 25 µg of HT-29 cell lysate stained with ARG40065 anti-FA2H antibody at 1:1000 dilution.
